Blog Archives

Loss of Weight – UpToDate

Loss of Weight Clinically important weight loss is traditionally defined as loss of more than 5 percent of usual body weight over six months. Major causes of weight loss 1) Voluntary weight loss Drugs Rx ↓ obesity: rimonabant, orlistat, phentermine, sibutramine,

Posted in 60 Loss of Wt, 99 Priority Topics, Endo, FM 99 priority topics

Fatigue – UpToDate

Fatigue can be manifested as difficulty or inability initiating activity (perception of generalized weakness); reduced capacity maintaining activity (easy fatiguability); and difficulty with concentration, memory, and emotional stability (mental fatigue) Fatigue should be distinguished from somnolence, dyspnea, and muscle weakness

Posted in 28 Fatigue, 99 Priority Topics, Endo, FM 99 priority topics

Obesity – CCPG 2006

1  In patients who appear to be obese, make the diagnosis of obesity using a clear definition (i.e., currently body mass index) and inform them of the diagnosis. BMI = kg/m² – poor predictor of obesity Should be measured in

Posted in 68 Obesity, 99 Priority Topics, Endo, FM 99 priority topics

Thyroid Disease – 2011 UofT FM Guideline & Uptodate

Overview Hypothalamus –> TRH – pituitary gland –> TSH, which controls the production of T3 & T4 from the thyroid gland. T3/T4 affects protein synthesis by affecting gene transcription and mRNA stabilization. They play an important role in regulating tissue metabolism

Posted in 91 Thyroid, 99 Priority Topics, Endo, FM 99 priority topics

Type 2 Diabetes – CDA 2013 Guidelines

1 Given a symptomatic or asymptomatic patient at high risk for diabetes (e.g., patients with gestational diabetes, obese, certain ethnic groups, and those with a strong family history), screen at appropriate intervals with the right tests to confirm the diagnosis.

Posted in 25 Diabetes, 99 Priority Topics, Endo, FM 99 priority topics

Osteoporosis – 2010 Guideline CMAJ

Focus on preventing fragility fracture Osteoporosis – T scoare <= -2.5 Indications for measuring BMD with dual-energy x-ray absorptiometry Age >= 65 Clinic risk factors for fracture (menopausal women, men 50-64yo) Fragility # after age 40yr High risk medications –

Posted in 69 Osteoporosis, 99 Priority Topics, Endo, FM 99 priority topics
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